Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mnod_2262KEGG: bja:blr2321 hypothetical protein. (340 aa)    
Predicted Functional Partners:
Mnod_1945
Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: met:M446_0317 beta-ketoacyl synthase.
 
 0.846
Mnod_2263
PFAM: aldo/keto reductase; KEGG: bcm:Bcenmc03_5778 aldo/keto reductase.
   
   0.492
leuD-2
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
  
    0.478
leuC-2
3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
  
    0.475
Mnod_2264
KEGG: met:M446_5598 hypothetical protein.
 
    
0.473
Mnod_0010
PFAM: protein of unknown function DUF29; KEGG: mrd:Mrad2831_1125 hypothetical protein.
    
  0.460
Mnod_2255
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: rsh:Rsph17029_4152 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  0.448
Mnod_5118
KEGG: met:M446_3024 hypothetical protein.
  
     0.443
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
     
 0.419
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.