Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
Mnod_2359Cytochrome c oxidase, subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (591 aa)    
Predicted Functional Partners:
Mnod_2358
PFAM: cytochrome c oxidase subunit II; KEGG: met:M446_3898 cytochrome c oxidase subunit II.
 
 0.995
Mnod_2347
TIGRFAM: cytochrome c oxidase, subunit II; PFAM: cytochrome c oxidase subunit II; cytochrome c class I; KEGG: met:M446_2991 cytochrome c oxidase, subunit II.
 
 0.993
Mnod_6886
TIGRFAM: cytochrome c oxidase, subunit II; PFAM: cytochrome c oxidase subunit II; cytochrome c class I; KEGG: met:M446_5817 cytochrome c oxidase, subunit II.
 
 0.992
Mnod_2361
PFAM: cytochrome c oxidase subunit III; KEGG: met:M446_3895 cytochrome c oxidase subunit III.
 
 0.990
Mnod_2360
PFAM: cytochrome c oxidase subunit III; KEGG: met:M446_3896 cytochrome c oxidase.
 
 0.986
Mnod_0260
Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
 0.980
Mnod_7536
Cytochrome b/b6 domain protein; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
 
 
 0.967
Mnod_0265
PFAM: cytochrome c oxidase subunit III; KEGG: met:M446_2344 cytochrome c oxidase subunit III.
 0.962
Mnod_4778
TIGRFAM: ubiquinol oxidase, subunit II; PFAM: cytochrome c oxidase subunit II; COX aromatic rich domain protein; KEGG: mex:Mext_4337 ubiquinol oxidase, subunit II.
 
 0.959
Mnod_6884
PFAM: cytochrome c oxidase subunit III; KEGG: met:M446_5815 cytochrome c oxidase subunit III.
 
 0.959
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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