Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mnod_2362KEGG: met:M446_3894 cytochrome c oxidase subunit IV. (110 aa)    
Predicted Functional Partners:
Mnod_2361
PFAM: cytochrome c oxidase subunit III; KEGG: met:M446_3895 cytochrome c oxidase subunit III.
 
   
 0.953
Mnod_2360
PFAM: cytochrome c oxidase subunit III; KEGG: met:M446_3896 cytochrome c oxidase.
 
   
 0.948
Mnod_2358
PFAM: cytochrome c oxidase subunit II; KEGG: met:M446_3898 cytochrome c oxidase subunit II.
 
   
 0.932
Mnod_2359
Cytochrome c oxidase, subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
 
     0.906
Mnod_6883
TIGRFAM: caa(3)-type oxidase, subunit IV; KEGG: mex:Mext_0225 caa(3)-type oxidase, subunit IV.
     
  0.900
Mnod_2357
KEGG: met:M446_3899 cytochrome c oxidase subunit I.
 
     0.578
Mnod_6772
PFAM: GYD family protein; KEGG: met:M446_6926 GYD family protein.
 
     0.561
Mnod_7537
Ubiquinol-cytochrome c reductase, iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
     
  0.500
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
Server load: low (24%) [HD]