Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mnod_2375PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: met:M446_1331 major facilitator transporter. (451 aa)    
Predicted Functional Partners:
Mnod_2374
TIGRFAM: muconolactone delta-isomerase; PFAM: Muconolactone delta-isomerase; KEGG: met:M446_1330 muconolactone delta-isomerase.
 
   
 0.693
Mnod_2369
TIGRFAM: benzoate 1,2-dioxygenase, small subunit; PFAM: aromatic-ring-hydroxylating dioxygenase beta subunit; KEGG: met:M446_1325 benzoate 1,2-dioxygenase, small subunit.
 
  
 0.664
Mnod_2373
TIGRFAM: muconate and chloromuconate cycloisomerase; PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: met:M446_1329 muconate and chloromuconate cycloisomerase.
 
   
 0.630
Mnod_2368
TIGRFAM: benzoate 1,2-dioxygenase, large subunit; PFAM: Rieske [2Fe-2S] domain protein; Aromatic-ring-hydroxylating dioxygenase, alpha subunit-like; KEGG: met:M446_1324 benzoate 1,2-dioxygenase, large subunit.
 
     0.618
Mnod_2370
PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: met:M446_1326 oxidoreductase FAD/NAD(P)-binding subunit.
 
   
 0.589
Mnod_2372
TIGRFAM: catechol 1,2-dioxygenase; PFAM: intradiol ring-cleavage dioxygenase; Catechol dioxygenase domain protein; KEGG: met:M446_1328 catechol 1,2-dioxygenase.
 
   
 0.586
Mnod_2371
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: met:M446_1327 short-chain dehydrogenase/reductase SDR.
 
     0.571
Mnod_2376
PFAM: protein of unknown function DUF849; KEGG: met:M446_1332 hypothetical protein.
  
    0.561
Mnod_7063
L-lactate transport; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family.
  
   
 0.502
aroE
Shikimate dehydrogenase substrate binding domain protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
 
    0.435
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.