Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_2548KEGG: met:M446_3312 general secretion pathway protein E. (442 aa)    
Predicted Functional Partners:
Mnod_2549
PFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: met:M446_3311 UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
 
   
 0.822
Mnod_2550
KEGG: met:M446_3310 multidrug resistance efflux pump-like protein.
 
  
 0.780
Mnod_4885
KEGG: xau:Xaut_3460 ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components-like protein.
  
     0.619
Mnod_3583
SMART: HNH nuclease; KEGG: rpi:Rpic_2339 HNH endonuclease.
  
    0.558
Mnod_0270
KEGG: met:M446_2339 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; Diverse 7TM receptor extracellular region 2; Diverse 7TM receptor transmembrane region; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAC repeat-containing protein.
  
  
 0.517
Mnod_4493
PFAM: Creatininase; KEGG: met:M446_4561 creatininase.
  
  
 0.515
Mnod_6354
KEGG: met:M446_5170 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; SMART: PAC repeat-containing protein.
  
 
 0.478
Mnod_6353
GAF sensor hybrid histidine kinase; PFAM: response regulator receiver; GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: met:M446_5171 GAF sensor hybrid histidine kinase.
  
 
 0.457
Mnod_6976
KEGG: nar:Saro_2700 phage-related protein endonuclease-like.
  
    0.445
Mnod_6716
KEGG: met:M446_6199 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s).
  
  
 0.430
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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