STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
Mnod_2801TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; histidine kinase HAMP region domain protein; KEGG: reh:H16_B1591 putative GGDEF family protein. (628 aa)    
Predicted Functional Partners:
Mnod_6353
GAF sensor hybrid histidine kinase; PFAM: response regulator receiver; GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: met:M446_5171 GAF sensor hybrid histidine kinase.
  
 
 0.822
Mnod_5340
PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; KEGG: met:M446_5034 response regulator receiver modulated metal dependent phosphohydrolase.
 
  
 0.787
Mnod_0144
KEGG: met:M446_2683 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
 
 0.767
Mnod_4585
KEGG: met:M446_3030 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
 
 0.765
Mnod_5453
CheA signal transduction histidine kinase; PFAM: response regulator receiver; CheW domain protein; ATP-binding region ATPase domain protein; Hpt domain protein; KEGG: met:M446_0244 CheA signal transduction histidine kinase.
 
  
 0.734
Mnod_6354
KEGG: met:M446_5170 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; SMART: PAC repeat-containing protein.
 
 
 0.730
Mnod_7465
KEGG: met:M446_6715 metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; Metal-dependent hydrolase HDOD; SMART: metal-dependent phosphohydrolase HD region.
 
 
 0.706
Mnod_1329
KEGG: met:M446_0917 metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region.
 
 
 0.703
Mnod_0270
KEGG: met:M446_2339 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; Diverse 7TM receptor extracellular region 2; Diverse 7TM receptor transmembrane region; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAC repeat-containing protein.
 
 
0.699
Mnod_1691
CheA signal transduction histidine kinase; PFAM: response regulator receiver; CheW domain protein; ATP-binding region ATPase domain protein; Signal transducing histidine kinase homodimeric; Hpt domain protein; KEGG: met:M446_4838 CheA signal transduction histidine kinase.
  
  
 0.672
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.