STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_2805PFAM: isochorismatase hydrolase; KEGG: met:M446_2408 isochorismatase hydrolase. (208 aa)    
Predicted Functional Partners:
nadE
NAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
 
 
 0.648
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
  
    0.610
gpsA
PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Ketopantoate reductase ApbA/PanE domain protein; KEGG: met:M446_4531 glycerol-3-phosphate dehydrogenase (NAD(P)(+)).
  
   0.550
Mnod_6547
Catalase domain protein; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family.
 
 
 0.485
Mnod_2804
KEGG: met:M446_2409 hypothetical protein.
       0.469
Mnod_1227
PFAM: Acetamidase/Formamidase; KEGG: met:M446_1631 acetamidase/formamidase.
 
     0.448
Mnod_2806
PFAM: transglutaminase family protein cysteine peptidase BTLCP; KEGG: met:M446_2407 transglutaminase family protein cysteine peptidase BTLCP.
       0.441
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
  
 0.440
Mnod_6082
KEGG: met:M446_5360 hypothetical protein.
  
     0.430
Mnod_2803
PFAM: type IV pilus assembly PilZ; KEGG: met:M446_2410 type IV pilus assembly PilZ.
 
     0.416
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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