Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_2894PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: met:M446_4912 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase. (286 aa)    
Predicted Functional Partners:
Mnod_2895
PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KEGG: met:M446_4913 short-chain dehydrogenase/reductase SDR.
  
  0.978
Mnod_7276
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: met:M446_6011 short-chain dehydrogenase/reductase SDR.
  
  0.933
Mnod_2255
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: rsh:Rsph17029_4152 short-chain dehydrogenase/reductase SDR; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
  0.909
Mnod_6623
PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: met:M446_4912 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase.
  
  
 
0.900
hmgA
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
  
  
 0.563
Mnod_0105
PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: bbt:BBta_0175 putative hydratase/decarboxylase.
  
  
 0.415
Mnod_0200
PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: rle:pRL120704 putative hydratase/decarboxylase.
  
  
 0.407
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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