Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_2908PFAM: Aldehyde Dehydrogenase; KEGG: rec:RHECIAT_PC0000542 putative aldehyde dehydrogenase (NAD(+)) protein; Belongs to the aldehyde dehydrogenase family. (487 aa)    
Predicted Functional Partners:
Mnod_2910
TIGRFAM: haloacid dehalogenase, type II; HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like); PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: azc:AZC_2033 putative dehalogenase.
 
  0.939
Mnod_2912
PFAM: aminotransferase class-III; KEGG: azc:AZC_2031 hypothetical protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
 0.927
Mnod_2175
TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; KEGG: met:M446_2475 methylmalonate-semialdehyde dehydrogenase.
  
  
 
0.921
Mnod_2521
TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; KEGG: mpo:Mpop_4215 methylmalonate-semialdehyde dehydrogenase.
  
  
 
0.920
Mnod_5387
TIGRFAM: zinc-binding alcohol dehydrogenase family protein; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: met:M446_6106 zinc-binding alcohol dehydrogenase family protein.
  
 0.920
Mnod_6150
PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: har:HEAR1610 putative alcohol dehydrogenase with NAD(P)-binding.
  
 0.920
Mnod_1158
PFAM: AMP-dependent synthetase and ligase; KEGG: met:M446_2199 AMP-dependent synthetase and ligase.
   
 0.915
Mnod_3983
PFAM: AMP-dependent synthetase and ligase; KEGG: rha:RHA1_ro06598 acetate--CoA ligase.
   
 0.915
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.915
Mnod_5499
PFAM: Aldehyde Dehydrogenase; KEGG: bbt:BBta_5124 putative aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.913
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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