Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_3063PFAM: alpha/beta hydrolase fold; KEGG: mrd:Mrad2831_1661 alpha/beta hydrolase fold. (295 aa)    
Predicted Functional Partners:
Mnod_1452
TIGRFAM: haloacid dehalogenase, type II; HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like); PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: met:M446_5307 haloacid dehalogenase, type II.
 
 
 0.928
Mnod_2910
TIGRFAM: haloacid dehalogenase, type II; HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like); PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: azc:AZC_2033 putative dehalogenase.
  
 
 0.912
Mnod_4408
TIGRFAM: haloacid dehalogenase, type II; HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like); PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: met:M446_3414 haloacid dehalogenase, type II.
  
 
 0.910
Mnod_6597
PFAM: alpha/beta hydrolase fold; KEGG: met:M446_6061 alpha/beta hydrolase fold.
  
  
 
0.910
Mnod_2908
PFAM: Aldehyde Dehydrogenase; KEGG: rec:RHECIAT_PC0000542 putative aldehyde dehydrogenase (NAD(+)) protein; Belongs to the aldehyde dehydrogenase family.
    
 0.901
Mnod_5499
PFAM: Aldehyde Dehydrogenase; KEGG: bbt:BBta_5124 putative aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family.
    
 0.901
leuD-3
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 
    0.854
Mnod_1945
Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: met:M446_0317 beta-ketoacyl synthase.
  
 0.825
leuC-3
3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
  
    0.770
Mnod_3060
PFAM: sodium:dicarboxylate symporter; KEGG: xau:Xaut_4744 sodium:dicarboxylate symporter; Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family.
       0.568
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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