STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mnod_3090TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; KEGG: bid:Bind_0630 pyruvate kinase; Belongs to the pyruvate kinase family. (479 aa)    
Predicted Functional Partners:
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 0.985
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family.
  
 0.979
Mnod_2174
PFAM: phosphate acetyl/butaryl transferase; malic protein domain protein; malic protein NAD-binding; KEGG: met:M446_2472 malate dehydrogenase.
  
 0.943
Mnod_2328
PFAM: phosphate acetyl/butaryl transferase; malic protein domain protein; malic protein NAD-binding; KEGG: met:M446_1243 malate dehydrogenase.
  
 0.943
Mnod_7102
PFAM: phosphate acetyl/butaryl transferase; malic protein domain protein; malic protein NAD-binding; KEGG: met:M446_6546 malate dehydrogenase.
  
 0.943
Mnod_7392
PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: met:M446_6648 FMN-dependent alpha-hydroxy acid dehydrogenase.
   
 
 0.921
pckA
Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
    
 0.915
Mnod_0414
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: met:M446_2089 thiamine pyrophosphate binding domain-containing protein; Belongs to the TPP enzyme family.
  
 0.913
Mnod_4503
KEGG: met:M446_4569 phosphoenolpyruvate carboxylase; Belongs to the PEPCase type 1 family.
     
 0.913
Mnod_7118
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
     
 0.913
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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