Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_3118RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; KEGG: mex:Mext_0458 sigma-70 family RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (234 aa)    
Predicted Functional Partners:
Mnod_4399
PFAM: response regulator receiver; Sigma-70 region 4 type 2; KEGG: met:M446_2725 response regulator receiver protein.
 
  
 0.710
Mnod_6531
PFAM: HWE histidine kinase; KEGG: met:M446_5922 signal transduction histidine kinase.
 
   
 0.588
Mnod_0965
KEGG: met:M446_1677 signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: histidine kinase HAMP region domain protein; HWE histidine kinase; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
  
 0.582
Mnod_5905
KEGG: met:M446_5290 signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: HWE histidine kinase; PAS fold-3 domain protein; PAS fold-4 domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
  
 0.536
Mnod_3638
RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; KEGG: met:M446_3933 ECF subfamily RNA polymerase sigma-24 factor.
  
   
 0.505
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.502
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.502
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.494
Mnod_3117
Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: ade:Adeh_2212 LysR family transcriptional regulator.
  
    0.474
Mnod_0324
Signal transduction histidine kinase; PFAM: GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase dimerisation/phosphoacceptor; KEGG: met:M446_2279 signal transduction histidine kinase.
 
   
 0.446
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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