Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_3140PFAM: isochorismatase hydrolase; KEGG: sme:SMa1821 hydrolase. (218 aa)    
Predicted Functional Partners:
Mnod_3141
PFAM: protein of unknown function DUF1427; KEGG: pde:Pden_3503 protein of unknown function DUF1427.
 
    0.947
Mnod_3142
PFAM: Amidohydrolase 3; KEGG: azc:AZC_3091 hypothetical protein.
 
     0.922
Mnod_3144
KEGG: bja:blr4262 hypothetical protein.
 
     0.813
Mnod_7551
PFAM: glycosyl transferase family 20; KEGG: met:M446_6822 alpha,alpha-trehalose-phosphate synthase (UDP-forming).
   
    0.723
Mnod_3143
KEGG: bja:blr4261 hypothetical protein.
  
    0.686
Mnod_3145
PFAM: protein of unknown function DUF1275; KEGG: bra:BRADO5122 hypothetical protein.
 
     0.628
Mnod_2843
TIGRFAM: flavoprotein WrbA; PFAM: NADPH-dependent FMN reductase; flavodoxin/nitric oxide synthase; KEGG: met:M446_2368 flavoprotein WrbA.
  
    0.622
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
  
    0.610
Mnod_3537
Transcriptional regulator, XRE family; KEGG: smd:Smed_2202 helix-turn-helix domain protein.
   
    0.578
Mnod_4437
Transcriptional regulator, XRE family; SMART: helix-turn-helix domain protein; KEGG: mpo:Mpop_0928 hypothetical protein.
   
    0.578
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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