Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_3201TIGRFAM: CRISPR-associated protein Cas5 family; PFAM: CRISPR-associated protein CT1976; KEGG: rru:Rru_A0345 CRISPR-associated Cas5e family protein. (253 aa)    
Predicted Functional Partners:
Mnod_5412
TIGRFAM: CRISPR-associated protein, Cse4 family; PFAM: CRISPR-associated protein CT1975; KEGG: gdi:GDI2207 hypothetical protein.
 
 
 0.986
Mnod_5414
TIGRFAM: CRISPR-associated protein, Cse1 family; PFAM: CRISPR-associated protein Cse1; KEGG: acr:Acry_1813 CRISPR-associated CSE1 family protein.
 
 
 0.971
Mnod_5415
TIGRFAM: CRISPR-associated helicase Cas3; PFAM: helicase domain protein; KEGG: acr:Acry_3314 CRISPR-associated helicase Cas3.
 
 
 0.941
Mnod_5413
TIGRFAM: CRISPR-associated protein, Cse2 family; PFAM: CRISPR-associated protein Cse2; KEGG: gdi:GDI2208 hypothetical protein.
 
 
 0.938
cas1
CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
  
 0.871
Mnod_5410
TIGRFAM: CRISPR-associated protein, Cse3 family; PFAM: CRISPR-associated protein CT1974; KEGG: acr:Acry_1809 CRISPR-associated CSE3 family protein.
 
  
 0.866
Mnod_5408
TIGRFAM: CRISPR-associated protein Cas2; KEGG: rru:Rru_A0168 hypothetical protein.
 
  
 0.822
Mnod_0794
KEGG: xac:XAC3837 hypothetical protein.
  
 
 0.763
Mnod_5411
TIGRFAM: CRISPR-associated protein Cas5 family; CRISPR-associated protein Cas5; KEGG: rru:Rru_A0171 CRISPR-associated Cas5e family protein.
  
     0.762
Mnod_3202
KEGG: met:M446_1583 hypothetical protein.
       0.499
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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