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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
Mnod_3264PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; KEGG: met:M446_2698 homoserine dehydrogenase. (440 aa)    
Predicted Functional Partners:
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
  
 0.986
Mnod_0110
TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; KEGG: met:M446_4746 aspartate kinase; Belongs to the aspartokinase family.
 
 0.974
Mnod_4918
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.966
metXA
Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine.
 
 0.962
metAS
Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family.
  
 
 0.955
thrB
TIGRFAM: homoserine kinase; PFAM: aminoglycoside phosphotransferase; KEGG: met:M446_6026 homoserine kinase; Belongs to the pseudomonas-type ThrB family.
 
  
 0.943
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
 
 0.932
Mnod_3930
PFAM: dihydrodipicolinate synthetase; KEGG: met:M446_3845 dihydrodipicolinate synthetase.
 
 
 0.921
Mnod_3957
PFAM: dihydrodipicolinate synthetase; KEGG: met:M446_3845 dihydrodipicolinate synthetase.
 
 
 0.921
Mnod_3972
PFAM: dihydrodipicolinate synthetase; KEGG: met:M446_3845 dihydrodipicolinate synthetase.
 
 
 0.921
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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