Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_3345PFAM: aldo/keto reductase; KEGG: xac:XAC1212 oxidoreductase. (300 aa)    
Predicted Functional Partners:
Mnod_7069
PFAM: PrkA serine kinase; PrkA AAA domain protein; KEGG: met:M446_6236 putative serine protein kinase, PrkA.
   
    0.627
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family.
  
 
 0.620
Mnod_0220
HAD-superfamily hydrolase, subfamily IIB; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
   
   0.589
Mnod_1945
Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: met:M446_0317 beta-ketoacyl synthase.
  
 
 0.554
Mnod_5855
PFAM: aldo/keto reductase; KEGG: met:M446_5334 aldo/keto reductase.
 
 
0.515
Mnod_1313
PFAM: aldo/keto reductase; KEGG: met:M446_0927 aldo/keto reductase.
 
 
0.508
Mnod_5196
PFAM: Alcohol dehydrogenase zinc-binding domain protein; KEGG: met:M446_4455 alcohol dehydrogenase.
   
 
 0.503
Mnod_6431
PFAM: aldo/keto reductase; KEGG: gdi:GDI0457 oxidoreductase (aldo/keto reductase) protein.
 
 
0.490
Mnod_2263
PFAM: aldo/keto reductase; KEGG: bcm:Bcenmc03_5778 aldo/keto reductase.
 
 
0.488
Mnod_4490
PFAM: aminoglycoside phosphotransferase; KEGG: met:M446_4558 aminoglycoside phosphotransferase.
   
    0.487
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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