Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_3362TIGRFAM: phenylacetic acid degradation protein paaN; PFAM: Aldehyde Dehydrogenase; KEGG: xau:Xaut_0904 phenylacetic acid degradation protein PaaN. (553 aa)    
Predicted Functional Partners:
Mnod_3360
PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: xau:Xaut_0906 3-hydroxyacyl-CoA dehydrogenase NAD-binding.
  
 0.835
Mnod_3361
TIGRFAM: acetyl-CoA acetyltransferase; beta-ketoadipyl CoA thiolase; PFAM: Thiolase; KEGG: xau:Xaut_0905 beta-ketoadipyl CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.781
Mnod_3363
TIGRFAM: phenylacetate degradation, enoyl-CoA hydratase paaB; PFAM: Enoyl-CoA hydratase/isomerase; KEGG: xau:Xaut_0903 enoyl-CoA hydratase.
 
 0.758
Mnod_3359
TIGRFAM: phenylacetic acid degradation protein paaN; PFAM: MaoC domain protein dehydratase; Aldehyde Dehydrogenase; KEGG: xau:Xaut_0907 bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase.
  
  
0.709
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family.
  
 
 0.539
Mnod_1170
PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: met:M446_1812 glutamate synthase (ferredoxin).
  
  
 0.519
Mnod_5524
TIGRFAM: phenylacetate degradation, enoyl-CoA hydratase paaB; PFAM: Enoyl-CoA hydratase/isomerase; KEGG: rpe:RPE_0998 enoyl-CoA hydratase.
 
 0.513
Mnod_3357
Transcriptional regulator, PaaX family; PFAM: PaaX domain protein; PaaX domain protein domain; KEGG: smd:Smed_4146 transcriptional regulator, PaaX family.
  
  
 0.509
Mnod_7200
Transcriptional regulator, PaaX family; TIGRFAM: phenylacetic acid degradation operon negative regulatory protein PaaX; PFAM: PaaX domain protein; PaaX domain protein domain; KEGG: bra:BRADO2518 phenylacetic acid degradation operon negative regulatory protein PaaX.
  
  
 0.495
Mnod_1441
Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
 
 
 0.491
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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