STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mnod_3569KEGG: met:M446_4090 putative bacteriophage-related protein. (172 aa)    
Predicted Functional Partners:
ruvC
Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
     
  0.900
Mnod_6984
KEGG: met:M446_4090 putative bacteriophage-related protein.
     
 
0.900
ruvA
Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
  
 
 0.878
Mnod_3568
PFAM: HNH endonuclease; KEGG: abc:ACICU_02213 hypothetical protein.
 
     0.817
Mnod_3570
KEGG: met:M446_4089 hypothetical protein.
       0.785
Mnod_3567
KEGG: mag:amb0461 hypothetical protein.
       0.777
Mnod_2477
KEGG: nwi:Nwi_0811 hypothetical protein.
  
     0.773
Mnod_3852
KEGG: mag:amb0371 hypothetical protein.
  
     0.773
Mnod_5776
KEGG: nwi:Nwi_0811 hypothetical protein.
  
     0.772
Mnod_6670
Hypothetical protein; KEGG: mms:mma_2764 phage terminase, large subunit.
  
     0.772
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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