Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_3614TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: met:M446_3953 cation diffusion facilitator family transporter. (332 aa)    
Predicted Functional Partners:
flhA
Flagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
       0.590
coaE
dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
  
    0.504
aroE-3
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
       0.470
Mnod_1274
Maf family protein; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
       0.469
Mnod_0801
KEGG: met:M446_0177 heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; YHS domain protein; E1-E2 ATPase-associated domain protein; SMART: TRASH domain protein.
 
  
 0.463
Mnod_7403
PFAM: multicopper oxidase type 1; multicopper oxidase type 2; multicopper oxidase type 3; KEGG: met:M446_6581 multicopper oxidase type 3.
 
  
 0.413
Mnod_1071
KEGG: met:M446_2103 FAD dependent oxidoreductase.
  
    0.410
Mnod_3429
PFAM: FAD dependent oxidoreductase; KEGG: scl:sce4944 putative monooxygenase.
  
    0.410
Mnod_6858
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: bbt:BBta_1076 putative oxidoreductase.
  
    0.410
Mnod_6873
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: bbt:BBta_1076 putative oxidoreductase.
  
    0.410
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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