Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mnod_3689PFAM: protein of unknown function DUF1446; KEGG: mrd:Mrad2831_4048 hypothetical protein. (444 aa)    
Predicted Functional Partners:
Mnod_3688
KEGG: met:M446_5609 hypothetical protein.
 
     0.965
Mnod_3690
TIGRFAM: citrate/H+ symporter, CitMHS family; PFAM: Citrate transporter; KEGG: met:M446_5611 CitMHS family citrate/H+ symporter.
 
     0.957
hmgA
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
  
 
 0.816
Mnod_3691
Transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; KEGG: met:M446_5612 LysR family transcriptional regulator.
 
     0.665
Mnod_0290
PFAM: carboxyl transferase; KEGG: met:M446_2317 propionyl-CoA carboxylase.
  
  
 0.645
Mnod_5510
PFAM: carboxyl transferase; KEGG: met:M446_3811 carboxyl transferase.
  
  
 0.645
Mnod_3154
TIGRFAM: malonate decarboxylase, gamma subunit; PFAM: malonate decarboxylase gamma subunit; KEGG: met:M446_6854 malonate decarboxylase, gamma subunit.
  
  
 0.628
Mnod_5972
PFAM: transcriptional coactivator/pterin dehydratase; KEGG: met:M446_5747 transcriptional coactivator/pterin dehydratase.
  
  
 0.519
Mnod_0291
PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: met:M446_2316 carbamoyl-phosphate synthase L chain ATP-binding.
  
  
 0.464
Mnod_0898
acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
  
 0.464
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.