Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_3704RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; KEGG: met:M446_5939 ECF subfamily RNA polymerase sigma-24 factor. (290 aa)    
Predicted Functional Partners:
Mnod_3703
Alkylhydroperoxidase-like protein, AhpD family; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
 
  
 0.956
Mnod_4483
KEGG: met:M446_4551 putative transmembrane anti-sigma factor.
 
 
 0.566
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.538
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.526
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.516
Mnod_7468
Transcriptional regulator, TetR family; PFAM: regulatory protein TetR; KEGG: mex:Mext_3418 regulatory protein TetR.
  
     0.485
Mnod_7641
NmrA family protein; PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; NmrA family protein; KEGG: reh:H16_B1406 predicted nucleoside-diphosphate-sugar epimerase.
 
     0.475
Mnod_1588
Transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; KEGG: met:M446_2777 AraC family transcriptional regulator.
  
  
 0.470
Mnod_3755
MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor; TIGRFAM: PAS sensor protein; PFAM: CheB methylesterase; MCP methyltransferase CheR-type; HWE histidine kinase; PAS fold-4 domain protein; KEGG: met:M446_6211 MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor.
  
 
 0.439
Mnod_0787
KEGG: met:M446_4787 putative transmembrane anti-sigma factor.
  
 
 0.424
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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