Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mnod_3707PFAM: Malate/L-lactate dehydrogenase; KEGG: mrd:Mrad2831_5976 malate/L-lactate dehydrogenase; Belongs to the LDH2/MDH2 oxidoreductase family. (329 aa)    
Predicted Functional Partners:
Mnod_3705
PFAM: SAF domain protein; KEGG: mrd:Mrad2831_5980 hypothetical protein.
 
  
 0.985
Mnod_3706
PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein; KEGG: mrd:Mrad2831_5979 altronate dehydratase.
 
  
 0.984
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
    
 0.915
Mnod_0890
PFAM: aminotransferase class I and II; KEGG: bpt:Bpet4447 aspartate aminotransferase.
     
 0.905
Mnod_1959
PFAM: aminotransferase class I and II; KEGG: met:M446_3821 aminotransferase class I and II.
     
 0.905
Mnod_4937
PFAM: Bile acid:sodium symporter; KEGG: met:M446_2649 bile acid:sodium symporter.
   
    0.808
Mnod_3708
Transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: mrd:Mrad2831_5975 GntR family transcriptional regulator.
     
 0.606
uxuA
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
  
    0.531
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
Server load: low (24%) [HD]