Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_3729Transcriptional regulator, DeoR family; PFAM: regulatory protein DeoR; Helix-turn-helix type 11 domain protein; KEGG: met:M446_4660 DeoR family transcriptional regulator. (267 aa)    
Predicted Functional Partners:
Mnod_1240
PFAM: FAD dependent oxidoreductase; KEGG: met:M446_1975 FAD dependent oxidoreductase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.
 
  
 0.869
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
 
  
 0.750
Mnod_4638
CoA-binding domain protein; PFAM: GCN5-related N-acetyltransferase; CoA-binding domain protein; KEGG: met:M446_2589 CoA-binding domain-containing protein.
    
   0.740
Mnod_1150
TIGRFAM: PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: met:M446_2191 PTS IIA-like nitrogen-regulatory protein PtsN.
 
  
 0.487
Mnod_3728
KEGG: met:M446_4659 hypothetical protein.
       0.475
Mnod_0199
Putative PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: mrd:Mrad2831_0203 putative PTS IIA-like nitrogen-regulatory protein PtsN.
 
  
 0.469
Mnod_0122
PFAM: Xylose isomerase domain protein TIM barrel; KEGG: met:M446_4755 4-hydroxyphenylpyruvate dioxygenase.
  
  
 0.447
Mnod_5601
PFAM: oxidoreductase domain protein; NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; Oxidoreductase domain; dTDP-4-dehydrorhamnose reductase; NmrA family protein; Male sterility domain; KEGG: ote:Oter_3247 oxidoreductase domain-containing protein.
  
  
 0.442
Mnod_3708
Transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: mrd:Mrad2831_5975 GntR family transcriptional regulator.
  
   
 0.419
Mnod_4538
PAS/PAC sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; KEGG: met:M446_3255 multi-sensor hybrid histidine kinase.
  
  
 0.404
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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