Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_3975PFAM: proline racemase; KEGG: met:M446_3837 proline racemase; Belongs to the proline racemase family. (322 aa)    
Predicted Functional Partners:
Mnod_1216
PFAM: ornithine cyclodeaminase/mu-crystallin; KEGG: met:M446_1826 ornithine cyclodeaminase.
 
  
 0.924
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
    
 0.915
Mnod_1441
Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
    
 0.909
Mnod_3966
PFAM: proline racemase; KEGG: met:M446_3837 proline racemase; Belongs to the proline racemase family.
  
  
 
0.901
Mnod_3972
PFAM: dihydrodipicolinate synthetase; KEGG: met:M446_3845 dihydrodipicolinate synthetase.
 
  
 0.824
Mnod_3970
PFAM: FAD dependent oxidoreductase; KEGG: met:M446_3847 FAD dependent oxidoreductase.
 
   
 0.801
Mnod_3973
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: nfa:nfa18910 putative ABC transporter ATP-binding protein.
  
  
 0.767
Mnod_3974
TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: azc:AZC_0817 ABC transporter permease protein.
  
    0.762
Mnod_4261
PFAM: FAD dependent oxidoreductase; KEGG: rso:RSc0507 amino acid dehydrogenase transmembrane protein.
 
   
 0.729
Mnod_3955
PFAM: FAD dependent oxidoreductase; KEGG: met:M446_3847 FAD dependent oxidoreductase.
 
   
 0.709
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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