Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mnod_4031KEGG: smd:Smed_6196 NodH sulfotransferase. (249 aa)    
Predicted Functional Partners:
Mnod_0201
PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; KEGG: alpha amylase 3 (IC).
  
     0.723
Mnod_2528
KEGG: bbt:BBta_4965 hypothetical protein.
  
     0.655
cysC
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate.
       0.590
Mnod_4030
ABC-2 type transporter, NodJ family; Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction. Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4- linked N-acetylglucosamine oligosaccharide. This subunit encodes the transporter.
       0.585
nodI
Nodulation ABC transporter NodI; Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction. Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4- linked N-acetylglucosamine oligosaccharide. This subunit is responsible for energy coupling to the transport system.
       0.578
Mnod_7227
KEGG: met:M446_6475 hypothetical protein.
  
     0.525
rppH
NUDIX hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily.
  
     0.512
Mnod_7293
Glutamate/cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
  
     0.498
Mnod_3823
KEGG: mrd:Mrad2831_5740 phage-type endonuclease.
  
     0.477
Mnod_5389
Hypothetical protein; KEGG: nmu:Nmul_A1222 von Willebrand factor, type A.
  
     0.469
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
Server load: low (26%) [HD]