Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_4179PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S9A prolyl oligopeptidase domain protein beta-propeller; KEGG: met:M446_4444 oligopeptidase B. (713 aa)    
Predicted Functional Partners:
Mnod_4178
PFAM: Fe-S metabolism associated SufE; KEGG: met:M446_4443 Fe-S metabolism associated SufE.
 
     0.605
Mnod_4751
Conserved hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
  
  
 0.454
Mnod_7360
PFAM: peptidase S9 prolyl oligopeptidase active site domain protein; peptidase S9A prolyl oligopeptidase domain protein beta-propeller; KEGG: met:M446_6607 peptidase S9 prolyl oligopeptidase.
 
  
0.414
Mnod_3862
Hypothetical protein; KEGG: saz:Sama_1832 electron transport complex protein RnfC.
   
  
 0.413
Mnod_5772
PFAM: peptidase S14 ClpP; KEGG: nha:Nham_2389 peptidase S14, ClpP; Belongs to the peptidase S14 family.
   
  
 0.413
Mnod_7330
PFAM: peptidase S14 ClpP; KEGG: pmy:Pmen_3971 peptidase S14, ClpP; Belongs to the peptidase S14 family.
   
  
 0.413
clpP
Peptidase S14 ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
   
  
 0.413
Mnod_4177
KEGG: met:M446_4442 signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: histidine kinase dimerisation/phosphoacceptor; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
  
    0.404
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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