Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_4265PFAM: Endoribonuclease L-PSP; KEGG: pap:PSPA7_6077 hypothetical protein. (116 aa)    
Predicted Functional Partners:
Mnod_4261
PFAM: FAD dependent oxidoreductase; KEGG: rso:RSc0507 amino acid dehydrogenase transmembrane protein.
 
    0.631
Mnod_4263
PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: reh:H16_B1829 ABC-type transporter, ATPase component: POPT family; Belongs to the ABC transporter superfamily.
       0.549
Mnod_4264
PFAM: extracellular solute-binding protein family 1; KEGG: azc:AZC_2475 extracellular solute-binding protein.
       0.546
Mnod_4262
PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: azc:AZC_2477 binding-protein-dependent transport systems inner membrane component.
       0.535
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.430
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
  
    0.421
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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