Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_4394PFAM: beta-lactamase domain protein; KEGG: met:M446_2731 beta-lactamase domain-containing protein. (304 aa)    
Predicted Functional Partners:
Mnod_7413
PFAM: NUDIX hydrolase; KEGG: met:M446_6674 NUDIX hydrolase.
 
 
   0.613
Mnod_0216
Protein of unknown function DUF882; PFAM: peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin; protein of unknown function DUF882; Peptidase M15A; KEGG: met:M446_3151 hypothetical protein.
 
    0.542
Mnod_4395
KEGG: met:M446_2730 molybdenum cofactor biosynthesis protein.
       0.531
Mnod_7566
KEGG: met:M446_6830 hypothetical protein.
  
     0.500
Mnod_5441
TIGRFAM: pimeloyl-CoA dehydrogenase, large subunit; PFAM: acyl-CoA dehydrogenase domain protein; KEGG: met:M446_0233 pimeloyl-CoA dehydrogenase, large subunit.
 
   0.469
Mnod_3391
TIGRFAM: sarcosine oxidase, alpha subunit family; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: mex:Mext_3738 sarcosine oxidase alpha subunit family protein.
  
 0.465
Mnod_5440
PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: met:M446_0232 acyl-CoA dehydrogenase domain-containing protein.
 
   0.440
Mnod_3636
PFAM: L-carnitine dehydratase/bile acid-inducible protein F; KEGG: met:M446_3935 L-carnitine dehydratase/bile acid-inducible protein F; Belongs to the CoA-transferase III family.
  
    0.417
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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