Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_4460PFAM: Cupin 2 conserved barrel domain protein; KEGG: met:M446_4530 cupin 2 domain-containing protein. (140 aa)    
Predicted Functional Partners:
Mnod_1393
KEGG: met:M446_0859 putative glucokinase.
  
     0.623
Mnod_5657
KEGG: met:M446_1942 tetratricopeptide TPR_4.
  
    0.580
Mnod_1603
PFAM: extracellular solute-binding protein family 5; KEGG: met:M446_0497 extracellular solute-binding protein.
  
     0.547
Mnod_1406
PFAM: PepSY-associated TM helix domain protein; KEGG: met:M446_0832 PepSY-associated TM helix domain-containing protein.
 
     0.504
Mnod_0007
PFAM: PepSY-associated TM helix domain protein; KEGG: rpb:RPB_4238 PepSY-associated TM helix.
 
     0.464
Mnod_6648
Putative phytochrome sensor protein; PFAM: protein of unknown function UPF0118; GAF domain protein; KEGG: ajs:Ajs_1892 putative GAF sensor protein.
 
    0.461
Mnod_1725
PFAM: protein of unknown function UPF0118; KEGG: met:M446_0413 hypothetical protein.
 
     0.453
Mnod_0756
Transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; KEGG: dac:Daci_1440 GntR family transcriptional regulator.
 
    0.445
Mnod_0300
KEGG: met:M446_2305 putative branched-chain amino acid ABC transport system substrate-binding protein.
  
     0.426
Mnod_0048
TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: met:M446_0048 MATE efflux family protein.
  
     0.417
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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