STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mnod_4476PFAM: protein of unknown function DUF1611; KEGG: met:M446_4542 hypothetical protein. (340 aa)    
Predicted Functional Partners:
Mnod_4475
PFAM: Mandelate racemase/muconate lactonizing protein; KEGG: met:M446_4541 mandelate racemase/muconate lactonizing protein.
 
  
  0.995
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
     
  0.900
murD
UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
     
  0.900
purQ
Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...]
     
  0.900
glsA
PFAM: Glutaminase, core; KEGG: met:M446_4570 glutaminase; Belongs to the glutaminase family.
     
  0.900
Mnod_5349
TIGRFAM: L-asparaginase, type II; PFAM: Asparaginase/glutaminase; KEGG: met:M446_5042 L-asparaginase, type II; Belongs to the asparaginase 1 family.
     
  0.900
Mnod_4477
PFAM: extracellular solute-binding protein family 3; KEGG: met:M446_4543 extracellular solute-binding protein.
       0.524
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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