Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mnod_4482PFAM: protein of unknown function UPF0005; KEGG: met:M446_4550 hypothetical protein; Belongs to the BI1 family. (236 aa)    
Predicted Functional Partners:
Mnod_4483
KEGG: met:M446_4551 putative transmembrane anti-sigma factor.
 
     0.693
Mnod_4484
RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: met:M446_4552 ECF subfamily RNA polymerase sigma-24 factor.
       0.649
Mnod_0998
PFAM: import inner membrane translocase subunit Tim44; KEGG: met:M446_1374 import inner membrane translocase subunit Tim44.
  
  
 0.551
Mnod_4485
TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase; KEGG: met:M446_4553 gamma-glutamyltransferase.
  
   0.493
Mnod_6611
PFAM: protein of unknown function DUF1013; KEGG: met:M446_6075 hypothetical protein.
  
     0.437
Mnod_1063
TIGRFAM: methionine-R-sulfoxide reductase; PFAM: Methionine sulfoxide reductase B; KEGG: met:M446_1425 methionine-R-sulfoxide reductase.
  
   0.432
yidC
YidC translocase/secretase; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
 
     0.422
Mnod_5842
PFAM: import inner membrane translocase subunit Tim44; KEGG: met:M446_5103 import inner membrane translocase subunit Tim44.
   
  
 0.412
priA
Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily.
 
     0.400
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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