Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
Mnod_4484RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70 region 4 type 2; KEGG: met:M446_4552 ECF subfamily RNA polymerase sigma-24 factor. (193 aa)    
Predicted Functional Partners:
Mnod_4483
KEGG: met:M446_4551 putative transmembrane anti-sigma factor.
 
 
 0.929
Mnod_4482
PFAM: protein of unknown function UPF0005; KEGG: met:M446_4550 hypothetical protein; Belongs to the BI1 family.
       0.649
Mnod_4485
TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase; KEGG: met:M446_4553 gamma-glutamyltransferase.
       0.605
Mnod_2754
KEGG: xau:Xaut_2661 putative transmembrane anti-sigma factor.
 
 
 0.568
Mnod_4399
PFAM: response regulator receiver; Sigma-70 region 4 type 2; KEGG: met:M446_2725 response regulator receiver protein.
 
  
 0.518
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.502
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.502
Mnod_0965
KEGG: met:M446_1677 signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: histidine kinase HAMP region domain protein; HWE histidine kinase; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
  
 0.494
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.494
Mnod_3638
RNA polymerase, sigma-24 subunit, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; KEGG: met:M446_3933 ECF subfamily RNA polymerase sigma-24 factor.
  
   
 0.467
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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