Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_4545TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; KEGG: met:M446_3071 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase. (216 aa)    
Predicted Functional Partners:
Mnod_4546
PFAM: PfkB domain protein; KEGG: met:M446_3070 ribokinase-like domain-containing protein.
 
 
 0.994
Mnod_5260
PFAM: Glucokinase; KEGG: met:M446_3296 glucokinase; Belongs to the bacterial glucokinase family.
 
 
 0.946
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family.
  
 
 0.919
Mnod_0677
PFAM: FAD linked oxidase domain protein; KEGG: met:M446_1765 FAD linked oxidase domain-containing protein.
   
 
 0.909
Mnod_4582
PFAM: FAD linked oxidase domain protein; KEGG: met:M446_3033 FAD linked oxidase domain-containing protein.
   
 
 0.909
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
     
 0.907
Mnod_0680
PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: met:M446_1761 hypothetical protein.
     
 0.906
Mnod_0378
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: met:M446_2232 glyoxylate reductase.
    
  0.905
Mnod_3087
TIGRFAM: glyoxylate carboligase; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: bte:BTH_I2173 glyoxylate carboligase; Belongs to the TPP enzyme family.
     
 0.905
Mnod_7113
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: met:M446_6553 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding.
    
  0.905
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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