STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mnod_4546PFAM: PfkB domain protein; KEGG: met:M446_3070 ribokinase-like domain-containing protein. (311 aa)    
Predicted Functional Partners:
Mnod_4545
TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; KEGG: met:M446_3071 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase.
 
 
 0.994
uxuA
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
 
  
 0.939
Mnod_1739
PFAM: ribulose-phosphate 3-epimerase; KEGG: met:M446_5429 ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family.
  
 0.865
Mnod_4805
PFAM: KDPG and KHG aldolase; KEGG: met:M446_4621 KDPG and KHG aldolase.
 
  
 0.858
hisA
TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein; KEGG: met:M446_6791 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
  
    0.738
Mnod_6583
PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein; SAF domain protein; KEGG: met:M446_6599 galactarate dehydratase.
 
  
 0.730
Mnod_0976
PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; KEGG: azc:AZC_3347 mannitol dehydrogenase.
 
   
 0.719
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family.
  
  
 0.598
Mnod_0647
Transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: azc:AZC_4468 putative transcriptional regulator.
 
  
 0.594
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.585
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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