Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mnod_4590PFAM: peptidase C15 pyroglutamyl peptidase I; KEGG: mex:Mext_0297 peptidase C15 pyroglutamyl peptidase I. (200 aa)    
Predicted Functional Partners:
Mnod_4175
PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: met:M446_4440 peptidase S1 and S6 chymotrypsin/Hap.
  
 
 
 0.780
Mnod_7561
KEGG: met:M446_6826 AAA family ATPase, CDC48 subfamily protein; TIGRFAM: AAA family ATPase, CDC48 subfamily; PFAM: AAA ATPase VAT domain protein; AAA ATPase central domain protein; cell division protein 48 CDC48 domain 2; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; Belongs to the AAA ATPase family.
    
   0.771
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
   0.761
Mnod_4589
PFAM: Amidase; KEGG: met:M446_4799 amidase.
       0.752
Mnod_1390
SMART: WD-40 repeat protein; KEGG: met:M446_0862 WD-40 repeat-containing protein.
   
   0.751
Mnod_5293
PFAM: WD-40 repeat protein; cytochrome c class I; KEGG: met:M446_3100 cytochrome c class I.
   
   0.751
Mnod_0636
KEGG: cyt:cce_5237 hypothetical protein.
  
   0.745
Mnod_2090
PFAM: Ankyrin; KEGG: met:M446_4648 ankyrin.
   
 
 0.741
Mnod_2960
Hypothetical protein.
   
 
 0.741
Mnod_0150
PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: met:M446_4609 peptidase S1 and S6 chymotrypsin/Hap.
    
 
 0.735
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
Server load: medium (48%) [HD]