Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_4608KEGG: met:M446_2617 UreA ABC transporter, ATP-binding protein UrtD; TIGRFAM: urea ABC transporter, ATP-binding protein UrtD; PFAM: ABC transporter related; SMART: AAA ATPase. (261 aa)    
Predicted Functional Partners:
Mnod_4607
TIGRFAM: urea ABC transporter, permease protein UrtC; PFAM: inner-membrane translocator; KEGG: met:M446_2618 UreA ABC transporter, permease protein UrtC; Belongs to the binding-protein-dependent transport system permease family.
 
 0.997
Mnod_4606
TIGRFAM: urea ABC transporter, permease protein UrtB; PFAM: inner-membrane translocator; KEGG: met:M446_2619 UreA ABC transporter, permease protein UrtB; Belongs to the binding-protein-dependent transport system permease family.
 
 
 0.996
Mnod_4605
TIGRFAM: urea ABC transporter, urea binding protein; KEGG: met:M446_2620 putative UreA short-chain amide.
 
 
 0.993
Mnod_4609
KEGG: met:M446_2616 UreA ABC transporter, ATP-binding protein UrtE; TIGRFAM: urea ABC transporter, ATP-binding protein UrtE; PFAM: ABC transporter related; SMART: AAA ATPase.
 
0.989
ureB
TIGRFAM: urease, beta subunit; urease, gamma subunit; PFAM: Urease beta subunit; Urease gamma subunit region; KEGG: met:M446_2213 urease, gamma subunit; Belongs to the urease beta subunit family.
 
  
 0.824
ureF
Urease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
   
 0.811
ureD
Urease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
   
 0.803
ureC
TIGRFAM: urease, alpha subunit; PFAM: amidohydrolase; Urease alpha-subunit domain protein; Amidohydrolase 3; KEGG: met:M446_2211 urease, alpha subunit.
 
   
 0.714
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
   
 0.708
ureE
UreE urease accessory domain protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
   
 0.696
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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