Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_4653PFAM: Xylose isomerase domain protein TIM barrel; KEGG: met:M446_2625 hydroxypyruvate isomerase; Belongs to the hyi family. (260 aa)    
Predicted Functional Partners:
Mnod_4654
PFAM: type III effector Hrp-dependent outers; KEGG: met:M446_2624 type III effector Hrp-dependent outers.
 
  
 0.926
Mnod_4652
PFAM: 6-phosphogluconate dehydrogenase NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; KEGG: met:M446_2626 3-hydroxyisobutyrate dehydrogenase.
 
  
 0.751
Mnod_4650
PFAM: class II aldolase/adducin family protein; KEGG: met:M446_2628 class II aldolase/adducin family protein.
 
  
 0.636
Mnod_7275
PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility domain; KEGG: met:M446_6012 NAD-dependent epimerase/dehydratase.
 
    0.585
Mnod_3087
TIGRFAM: glyoxylate carboligase; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; KEGG: bte:BTH_I2173 glyoxylate carboligase; Belongs to the TPP enzyme family.
 
  
 0.535
Mnod_4651
Transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: met:M446_2627 LacI family transcription regulator.
       0.439
Mnod_0654
PFAM: MOFRL domain protein; KEGG: mpo:Mpop_4659 hydroxypyruvate reductase.
 
  
 0.417
Mnod_2419
PFAM: type III effector Hrp-dependent outers; KEGG: pol:Bpro_0094 type III effector Hrp-dependent outers.
 
  
 0.413
Mnod_5964
PFAM: MOFRL domain protein; KEGG: met:M446_5205 hydroxypyruvate reductase.
 
  
 0.408
Mnod_3436
PFAM: type III effector Hrp-dependent outers; KEGG: met:M446_1733 type III effector Hrp-dependent outers.
 
  
 0.400
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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