Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_4733TIGRFAM: carboxyl-terminal protease; PFAM: PDZ/DHR/GLGF domain protein; peptidase S41; KEGG: met:M446_4223 carboxyl-terminal protease; Belongs to the peptidase S41A family. (440 aa)    
Predicted Functional Partners:
Mnod_4732
PFAM: Peptidase M23; KEGG: met:M446_4222 peptidase M23B.
 
  
 0.959
rlmH
Protein of unknown function DUF163; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family.
       0.853
Mnod_3499
PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide domain protein; KEGG: mlo:mll2209 hypothetical protein.
  
 
 0.852
Mnod_4380
PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: met:M446_2747 TPR repeat-containing protein.
 
 
 0.832
rsfS
Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
   
   0.816
Mnod_1116
PFAM: NLP/P60 protein; KEGG: met:M446_2154 NLP/P60 protein.
    
 
 0.762
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
   0.700
Mnod_4734
PFAM: protein of unknown function DUF610 YibQ; KEGG: met:M446_4224 protein of unknown function DUF610 YibQ.
       0.667
Mnod_1532
KEGG: met:M446_0637 membrane-associated zinc metalloprotease; TIGRFAM: membrane-associated zinc metalloprotease; PFAM: peptidase M50; SMART: PDZ/DHR/GLGF domain protein.
 
  
 0.604
Mnod_2315
PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; TPR repeat-containing protein; Tetratricopeptide TPR_4; SMART: Tetratricopeptide domain protein; KEGG: met:M446_6439 TPR repeat-containing adenylate/guanylate cyclase.
  
 
 0.601
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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