STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mnod_4784PFAM: protein of unknown function DUF485; KEGG: met:M446_2953 hypothetical protein. (102 aa)    
Predicted Functional Partners:
Mnod_4785
TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; KEGG: met:M446_2954 SSS family solute/sodium (Na+) symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
  
 0.987
Mnod_3160
TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; KEGG: met:M446_3911 SSS family solute/sodium (Na+) symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
  
 0.947
Mnod_5210
TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; KEGG: met:M446_2954 SSS family solute/sodium (Na+) symporter.
 
  
 0.947
Mnod_0046
PFAM: cyclic nucleotide-binding; CBS domain containing protein; protein of unknown function DUF294 nucleotidyltransferase putative; KEGG: met:M446_0046 CBS domain-containing protein.
 
  
 0.847
Mnod_0045
PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: met:M446_0045 exonuclease RNase T and DNA polymerase III.
 
    0.775
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 0.755
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
   
    0.664
Mnod_5208
TIGRFAM: acetate/CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: met:M446_2952 acetate--CoA ligase.
  
  
 0.482
Mnod_4786
PFAM: beta-lactamase domain protein; KEGG: mex:Mext_0984 beta-lactamase-like protein.
       0.463
Mnod_1158
PFAM: AMP-dependent synthetase and ligase; KEGG: met:M446_2199 AMP-dependent synthetase and ligase.
  
  
 0.456
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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