close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mnod_4792PFAM: Protein-tyrosine phosphatase, low molecular weight; KEGG: met:M446_2636 protein tyrosine phosphatase. (155 aa)    
Predicted Functional Partners:
Mnod_4791
PFAM: conserved hypothetical protein; KEGG: met:M446_2637 hypothetical protein; Belongs to the UPF0262 family.
     0.901
Mnod_5682
PFAM: Protein-tyrosine phosphatase, low molecular weight; KEGG: mex:Mext_1909 low molecular weight phosphotyrosine protein phosphatase.
  
     0.706
Mnod_5722
PFAM: Protein-tyrosine phosphatase, low molecular weight; KEGG: mex:Mext_1909 low molecular weight phosphotyrosine protein phosphatase.
  
     0.706
hisD-2
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
       0.516
Mnod_1625
TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: met:M446_0473 thioredoxin; Belongs to the thioredoxin family.
  
 
 0.450
Mnod_3933
TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: met:M446_4174 thioredoxin; Belongs to the thioredoxin family.
  
 
 0.450
Mnod_4793
TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: met:M446_2635 O-acetylhomoserine/O-acetylserine sulfhydrylase.
       0.450
Mnod_5011
TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: met:M446_4174 thioredoxin; Belongs to the thioredoxin family.
  
 
 0.450
Mnod_5188
TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: met:M446_4464 thioredoxin.
  
 
 0.450
Mnod_1945
Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: met:M446_0317 beta-ketoacyl synthase.
  
 
 0.412
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.