STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mnod_4792PFAM: Protein-tyrosine phosphatase, low molecular weight; KEGG: met:M446_2636 protein tyrosine phosphatase. (155 aa)    
Predicted Functional Partners:
Mnod_4791
PFAM: conserved hypothetical protein; KEGG: met:M446_2637 hypothetical protein; Belongs to the UPF0262 family.
     0.932
Mnod_5682
PFAM: Protein-tyrosine phosphatase, low molecular weight; KEGG: mex:Mext_1909 low molecular weight phosphotyrosine protein phosphatase.
  
     0.706
Mnod_5722
PFAM: Protein-tyrosine phosphatase, low molecular weight; KEGG: mex:Mext_1909 low molecular weight phosphotyrosine protein phosphatase.
  
     0.706
hisD-2
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
    0.686
Mnod_4928
KEGG: met:M446_2639 hypothetical protein.
 
     0.536
Mnod_4793
TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: met:M446_2635 O-acetylhomoserine/O-acetylserine sulfhydrylase.
       0.451
Mnod_1945
Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: met:M446_0317 beta-ketoacyl synthase.
  
 
 0.440
Mnod_4933
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
 
    0.427
engB
GTP-binding protein HSR1-related; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
  
    0.422
Mnod_1625
TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: met:M446_0473 thioredoxin; Belongs to the thioredoxin family.
  
 
 0.416
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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