STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mnod_4822PFAM: formyl transferase domain protein; KEGG: met:M446_2572 methionyl-tRNA formyltransferase. (310 aa)    
Predicted Functional Partners:
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
 
  
 0.940
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
  
  
 
0.923
fhs
PFAM: formate-tetrahydrofolate ligase FTHFS; KEGG: met:M446_3236 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family.
    
 0.918
purH
TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region; KEGG: met:M446_2965 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase.
    
 0.915
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
     
 0.912
Mnod_1761
PFAM: formyl transferase domain protein; KEGG: met:M446_5456 formyl transferase domain-containing protein.
     
 0.908
Mnod_1943
PFAM: formyl transferase domain protein; KEGG: met:M446_0319 formyl transferase domain-containing protein.
     
  0.900
Mnod_5499
PFAM: Aldehyde Dehydrogenase; KEGG: bbt:BBta_5124 putative aldehyde dehydrogenase family protein; Belongs to the aldehyde dehydrogenase family.
 
      0.898
nusB
NusB antitermination factor; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
  
  
 0.775
Mnod_3732
TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: Aldehyde Dehydrogenase; KEGG: pst:PSPTO_0257 succinate-semialdehyde dehydrogenase.
 
      0.760
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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