Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
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textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Score
Mnod_4841KEGG: met:M446_4051 putative PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; PFAM: PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein. (143 aa)    
Predicted Functional Partners:
Mnod_6353
GAF sensor hybrid histidine kinase; PFAM: response regulator receiver; GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: met:M446_5171 GAF sensor hybrid histidine kinase.
 
 
 0.865
Mnod_6354
KEGG: met:M446_5170 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; SMART: PAC repeat-containing protein.
 
 
 0.810
frc-2
formyl-CoA transferase; Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl- CoA to oxalate; Belongs to the CoA-transferase III family. Frc subfamily.
 
     0.773
Mnod_3755
MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor; TIGRFAM: PAS sensor protein; PFAM: CheB methylesterase; MCP methyltransferase CheR-type; HWE histidine kinase; PAS fold-4 domain protein; KEGG: met:M446_6211 MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor.
 
  
 0.574
Mnod_6212
KEGG: mpo:Mpop_4776 PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
 
 0.555
Mnod_3507
PAS/PAC sensor hybrid histidine kinase; KEGG: pzu:PHZ_c2659 FOG: PAS/PAC domain protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
 
 0.502
Mnod_4538
PAS/PAC sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; KEGG: met:M446_3255 multi-sensor hybrid histidine kinase.
  
 
 0.493
Mnod_4585
KEGG: met:M446_3030 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
 
 0.489
Mnod_0144
KEGG: met:M446_2683 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Hpt domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
 
 0.478
Mnod_5453
CheA signal transduction histidine kinase; PFAM: response regulator receiver; CheW domain protein; ATP-binding region ATPase domain protein; Hpt domain protein; KEGG: met:M446_0244 CheA signal transduction histidine kinase.
 
 
 0.457
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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