STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mnod_4910N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; PFAM: Peptidoglycan-binding domain 1 protein; N-acetylmuramoyl-L-alanine amidase family 2; KEGG: met:M446_4374 N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD. (249 aa)    
Predicted Functional Partners:
Mnod_4909
PFAM: heat shock protein DnaJ domain protein; protein of unknown function DUF1332; KEGG: met:M446_4375 heat shock protein DnaJ domain-containing protein.
     
 0.862
Mnod_2180
PFAM: glycoside hydrolase family 3 domain protein; KEGG: met:M446_2482 beta-N-acetylhexosaminidase.
 
   
 0.627
Mnod_4908
KEGG: met:M446_4376 hypothetical protein.
     
 0.610
anmK
Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.
  
   
 0.574
Mnod_3755
MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor; TIGRFAM: PAS sensor protein; PFAM: CheB methylesterase; MCP methyltransferase CheR-type; HWE histidine kinase; PAS fold-4 domain protein; KEGG: met:M446_6211 MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor.
  
  
 0.542
Mnod_1606
PFAM: aminoglycoside phosphotransferase; protein of unknown function UPF0079; protein of unknown function DUF227; KEGG: met:M446_0493 aminoglycoside phosphotransferase.
  
   
 0.519
Mnod_1607
PFAM: Nucleotidyl transferase; KEGG: met:M446_0492 nucleotidyl transferase.
  
   
 0.490
Mnod_3113
Hypothetical protein; KEGG: mrd:Mrad2831_1648 major facilitator transporter.
 
   
 0.452
Mnod_5469
PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; KEGG: met:M446_0261 peptidoglycan glycosyltransferase.
     
 0.429
murD
UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
 
   
 0.421
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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