STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mnod_4911PFAM: aminotransferase class V; KEGG: met:M446_4373 serine--glyoxylate transaminase. (397 aa)    
Predicted Functional Partners:
Mnod_0115
PFAM: FAD dependent oxidoreductase; KEGG: met:M446_4751 sarcosine oxidase.
  
 
 0.930
Mnod_3393
TIGRFAM: sarcosine oxidase, beta subunit family; PFAM: FAD dependent oxidoreductase; KEGG: mrd:Mrad2831_2487 sarcosine oxidase beta subunit family protein.
  
 
 0.930
Mnod_7113
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: met:M446_6553 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding.
  
 
 0.926
Mnod_3391
TIGRFAM: sarcosine oxidase, alpha subunit family; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: mex:Mext_3738 sarcosine oxidase alpha subunit family protein.
  
 
 0.925
Mnod_7392
PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; KEGG: met:M446_6648 FMN-dependent alpha-hydroxy acid dehydrogenase.
  
 0.925
Mnod_6035
TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: met:M446_3526 glycine cleavage system T protein.
  
 
 0.920
Mnod_1511
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: met:M446_0667 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding.
  
 
 0.919
Mnod_2906
PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: mlo:mll7048 dehydrogenase.
  
 
 0.919
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.919
glyA-2
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.919
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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