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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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Mnod_4932TIGRFAM: 5-aminolevulinic acid synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; aminotransferase class-III; KEGG: met:M446_2643 5-aminolevulinic acid synthase. (414 aa)    
Predicted Functional Partners:
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
 
 0.948
Mnod_3391
TIGRFAM: sarcosine oxidase, alpha subunit family; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: mex:Mext_3738 sarcosine oxidase alpha subunit family protein.
  
 
 0.945
Mnod_7570
PFAM: delta-aminolevulinic acid dehydratase; KEGG: met:M446_6834 porphobilinogen synthase; Belongs to the ALAD family.
    
 0.919
Mnod_1169
Aromatic amino acid beta-eliminating lyase/threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
  
 
 0.913
Mnod_4807
PFAM: aminotransferase class-III; KEGG: met:M446_4623 aminotransferase class-III.
     
 0.912
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.911
glyA-2
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.911
Mnod_2767
PFAM: aminotransferase class V; KEGG: met:M446_3486 serine--glyoxylate transaminase.
    
 0.906
Mnod_3398
PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein; KEGG: mpo:Mpop_4001 NADH:flavin oxidoreductase/NADH oxidase.
  
 
 0.906
Mnod_4911
PFAM: aminotransferase class V; KEGG: met:M446_4373 serine--glyoxylate transaminase.
    
 0.906
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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