Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-expression
Experiments
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[Homology]
Score
Mnod_4958PFAM: conserved hypothetical protein; KEGG: met:M446_4930 hypothetical protein. (146 aa)    
Predicted Functional Partners:
Mnod_4959
KEGG: met:M446_4931 hypothetical protein.
       0.754
Mnod_5169
TIGRFAM: conserved hypothetical membrane protein; KEGG: met:M446_4482 hypothetical protein.
  
     0.527
Mnod_4759
KEGG: met:M446_4250 putative ICC-like phosphoesterase.
  
     0.525
Mnod_5564
PFAM: DNA polymerase III chi subunit HolC; KEGG: met:M446_5406 DNA polymerase III chi subunit HolC.
  
     0.525
yacG
Protein of unknown function DUF329; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase.
  
     0.522
Mnod_4374
KEGG: met:M446_2754 hypothetical protein.
  
     0.522
Mnod_4962
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: met:M446_4934 ABC transporter related.
 
     0.501
Mnod_4957
KEGG: mrd:Mrad2831_0649 hypothetical protein.
       0.498
Mnod_7422
PFAM: GcrA cell cycle regulator; KEGG: met:M446_6684 GcrA cell cycle regulator.
  
     0.488
Mnod_7413
PFAM: NUDIX hydrolase; KEGG: met:M446_6674 NUDIX hydrolase.
  
     0.478
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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