STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Mnod_4967Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; CI repressor; Cupin 2 conserved barrel domain protein; KEGG: met:M446_4938 XRE family transcriptional regulator. (218 aa)    
Predicted Functional Partners:
Mnod_4968
TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; KEGG: met:M446_4939 phosphomethylpyrimidine kinase.
  
    0.731
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
       0.731
Mnod_2705
PFAM: BFD domain protein [2Fe-2S]-binding domain protein; KEGG: mrd:Mrad2831_0112 hypothetical protein.
  
     0.672
Mnod_1519
PFAM: BFD domain protein [2Fe-2S]-binding domain protein; KEGG: met:M446_0656 hypothetical protein.
  
     0.603
Mnod_6132
PFAM: BFD domain protein [2Fe-2S]-binding domain protein; KEGG: met:M446_0656 hypothetical protein.
  
     0.603
Mnod_1090
KEGG: met:M446_2118 hypothetical protein.
  
     0.595
Mnod_4668
KEGG: met:M446_4778 hypothetical protein.
  
     0.577
Mnod_0728
PFAM: Chorismate mutase; KEGG: met:M446_1107 chorismate mutase.
 
   
 0.557
Mnod_1641
KEGG: met:M446_0456 hypothetical protein.
  
     0.548
Mnod_0393
KEGG: met:M446_2218 hypothetical protein.
  
     0.539
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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