Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_4971PFAM: metallophosphoesterase; KEGG: met:M446_4942 metallophosphoesterase. (290 aa)    
Predicted Functional Partners:
Mnod_4972
PFAM: glycosyl transferase group 1; KEGG: met:M446_4943 glycosyl transferase group 1.
     0.980
Mnod_4721
KEGG: met:M446_4208 hypothetical protein.
 
    0.586
Mnod_4970
PFAM: protein of unknown function DUF6 transmembrane; KEGG: met:M446_4941 hypothetical protein.
 
    0.567
Mnod_6079
Ribonuclease HII/HIII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
     
 0.503
lpxB
lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
     
 0.486
Mnod_7564
Three-deoxy-D-manno-octulosonic-acid transferase domain protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
     
 0.456
lpxK
Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
     
 0.438
Mnod_1861
PFAM: lipid A biosynthesis acyltransferase; KEGG: met:M446_4861 lipid A biosynthesis acyltransferase.
     
 0.427
Mnod_1252
TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); KEGG: met:M446_1995 KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily.
  
  
 0.425
Mnod_4432
PFAM: phospholipid/glycerol acyltransferase; KEGG: met:M446_3391 phospholipid/glycerol acyltransferase.
 
  
 0.424
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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