Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mnod_5155KEGG: met:M446_4498 hypothetical protein. (249 aa)    
Predicted Functional Partners:
Mnod_5156
KEGG: met:M446_4497 hypothetical protein.
 
  
 0.993
dnaE2
DNA polymerase III, alpha subunit; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.
 
  
 0.950
Mnod_0555
KEGG: mrd:Mrad2831_6255 DNA-directed DNA polymerase.
  
  
 0.775
Mnod_4994
Hypothetical protein; KEGG: mex:Mext_3517 DNA-directed DNA polymerase.
  
  
 0.775
Mnod_6837
Hypothetical protein; KEGG: mex:Mext_3517 DNA-directed DNA polymerase.
  
  
 0.775
Mnod_7046
PFAM: UMUC domain protein DNA-repair protein; KEGG: mrd:Mrad2831_6255 DNA-directed DNA polymerase.
  
  
 0.775
dinB
UMUC domain protein DNA-repair protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
  
  
 0.775
Mnod_7295
KEGG: met:M446_5992 DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; DNA polymerase III alpha subunit; SMART: phosphoesterase PHP domain protein.
  
  
 0.551
Mnod_7433
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
   
  
 0.486
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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