Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mnod_5210TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; KEGG: met:M446_2954 SSS family solute/sodium (Na+) symporter. (563 aa)    
Predicted Functional Partners:
Mnod_5209
PFAM: protein of unknown function DUF485; KEGG: met:M446_2953 hypothetical protein.
 
  
 0.987
Mnod_4784
PFAM: protein of unknown function DUF485; KEGG: met:M446_2953 hypothetical protein.
 
  
 0.947
Mnod_3159
PFAM: protein of unknown function DUF485; KEGG: met:M446_3910 hypothetical protein.
 
  
 0.940
Mnod_0046
PFAM: cyclic nucleotide-binding; CBS domain containing protein; protein of unknown function DUF294 nucleotidyltransferase putative; KEGG: met:M446_0046 CBS domain-containing protein.
 
  
 0.883
Mnod_0045
PFAM: Exonuclease RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: met:M446_0045 exonuclease RNase T and DNA polymerase III.
 
    0.749
Mnod_5208
TIGRFAM: acetate/CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: met:M446_2952 acetate--CoA ligase.
  
  
 0.728
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 0.423
Your Current Organism:
Methylobacterium nodulans
NCBI taxonomy Id: 460265
Other names: M. nodulans ORS 2060, Methylobacterium nodulans ORS 2060, Methylobacterium nodulans str. ORS 2060, Methylobacterium nodulans strain ORS 2060
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